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The risk of famine in Gaza is increasing with the deliberate withholding of humanitarian aid, including food, in the ongoing blockade.

The entire 2.1 million population of Gaza is facing prolonged food shortages, with nearly half a million people in a catastrophic situation of hunger, acute malnutrition, starvation, illness and death. This is one of the world’s worst hunger crises, unfolding in real time.

The latest food security analysis was released today by the Integrated Food Security Phase Classification (IPC) partnership, of which WHO is a member.

“We do not need to wait for a declaration of famine in Gaza to know that people are already starving, sick and dying, while food and medicines are minutes away across the border,” said WHO Director-General Dr Tedros Adhanom Ghebreyesus. “Today’s report shows that without immediate access to food and essential supplies, the situation will continue to deteriorate, causing more deaths and descent into famine.”

Famine has not yet been declared, but people are starving now. Three quarters of Gaza’s population are at “Emergency” or “Catastrophic” food deprivation, the worst two levels of IPC's five level scale of food insecurity and nutritional deprivation.

Since the aid blockade began on 2 March 2025, 57 children have reportedly died from the effects of malnutrition, according to the Ministry of Health. This number is likely an underestimate and is likely to increase.  If the situation persists, nearly 71 000 children under the age of five are expected to be acutely malnourished over the next eleven months, according to the IPC report.

People in Gaza are trapped in a dangerous cycle where malnutrition and disease fuel each other, turning everyday illness into a potential death sentence, particularly for children. Malnutrition weakens the bodies, making it harder to heal from injuries and fight off common communicable diseases like diarrhoea, pneumonia, and measles. In turn, these infections increase the body’s requirement for nutrition, while reducing nutrient intake and absorption, resulting in worsening malnutrition. With health care out of reach, vaccine coverage plummeting, access to clean water and sanitation severely limited, and increased child protection concerns, the risk of severe illness and death grows, especially for children suffering from severe acute malnutrition, who urgently need treatment to survive.

Pregnant and breastfeeding mothers are also at high risk of malnutrition, with nearly 17 000 expected to require treatment for acute malnutrition over the next eleven months, if the dire situation does not change. Malnourished mothers struggle to produce enough nutritious milk, putting their babies at risk, while the delivery of counselling services for mothers is heavily compromised. For infants under six months, breastmilk is their best protection against hunger and disease – especially where clean water is scarce, as it is in Gaza.

The long-term impact and damage from malnutrition can last a lifetime in the form of stunted growth, impaired cognitive development, and poor health. Without enough nutritious food, clean water, and access to health care, an entire generation will be permanently affected.

The plan recently announced by Israeli authorities to deliver food and other essential items across Gaza via proposed distribution sites is grossly inadequate to meet the immediate needs of over two million people. WHO echoes the UN’s call for the global humanitarian principles of humanity, impartiality, independence and neutrality to be upheld and respected and for unimpeded humanitarian access to be granted to provide aid based on people’s needs, wherever they may be. A well-established and proven humanitarian coordination system, led by the UN and its partners, is already in place and must be allowed to function fully to ensure that aid is delivered in a principled, timely, and equitable manner.

The aid blockade and shrinking humanitarian access continue to undermine WHO’s ability to support 16 outpatient and three inpatient malnutrition treatment centres with life-saving supplies, and to sustain the broader health system. The remaining supplies in WHO’s stocks inside Gaza are only enough to treat 500 children with acute malnutrition – a fraction of the urgent need – while essential medicines and supplies to treat diseases and trauma injuries are already running out and cannot be replenished due to the blockade.

People are dying while WHO and partners’ life-saving medical supplies sit just outside Gaza – ready for deployment, with safeguards in place to ensure the aid reaches those who need it most in line with humanitarian principles. WHO calls for the protection of health care and for an immediate end to the aid blockade, which is starving people, obstructing their right to health, and robbing them of dignity and hope. WHO calls for the release of all hostages, and for a ceasefire, which leads to lasting peace. 

The World Health Organization (WHO) Results Report 2024, shows progress on global health goals, even in times of growing financial uncertainties.

The report, released ahead of the Seventy-eight World Health Assembly (19–27 May 2025), presents a mid-term assessment of WHO’s performance in implementing the Programme budget 2024–2025, providing a snapshot of progress towards the strategic priorities of the Thirteenth General Programme of Work, 2019–2025.

The report highlights WHO’s work in over 150 countries, territories and provides an update on the implementation of the Thirteenth General Programme of Work, showcasing both the achievements so far and challenges ahead.

“This report shows how, with WHO’s support, many countries are making progress on a huge range of health indicators, helping their populations to live healthier lives, giving them greater access to essential health services, and keeping them safer against health emergencies,” said Dr Tedros Adhanom Ghebreyesus, WHO Director-General. “In a world of multiple overlapping challenges and constrained resources for global health, these results demonstrate why the world needs a strong and sustainably-financed WHO, delivering the high-quality, trusted support on which countries and their people rely.”

The report shows significant progress on coverage with essential health services, protection from health emergencies, and enjoyment of healthier lives. Still, the progress is insufficient to reach the health-related Sustainable Development Goals by 2030.

On the first billion – 1 billion more people benefitting from universal health coverage – an estimated 431 million more people, close to half of the goal, are estimated to be covered with essential health services without catastrophic health spending. This progress is largely driven by improvements in the healthcare workforce, increased access to contraception and expanded HIV antiretroviral therapy. However, people continue to face financial hardships and challenges in immunization programmes persist.

Regarding the second billion – 1 billion more people better protected from health emergencies – an estimated 637 million more people are better protected through stronger preparedness, surveillance, workforce capacity, and equitable access to tools and services, supported by reforms such as the amendments to the International Health Regulations. Yet financial constraints threaten pandemic response efforts. In the face of the H5N1 avian flu outbreak, there is a continued need for pandemic preparedness. After more than three years of negotiations, WHO member states have drafted a pandemic agreement that will be up for consideration at the upcoming World Health Assembly. The draft proposal includes measures for an increased research infrastructure, emergency global health workforces and other key mechanisms to prevent and respond to pandemic threats.

For the third billion – 1 billion more people enjoying better health and well-being – the report shows that 1.4 billion more people are living with better health and well-being, surpassing the initial goal. This is due to reduced tobacco use, improved air quality, clean household fuels, and access to water, sanitation and hygiene (WASH). Key challenges lie in addressing increased obesity and alcohol consumption.

However, reaching the goals faces growing challenges. Pause in foreign aid and reduction of health budgets further strain already fragile health systems, especially in communities with the greatest health needs. Financial constraints threaten pandemic response efforts. Reduced funding will also undermine hard-won progress.

WHO has taken concrete steps to become more efficient and effective, including by improving operational efficiency and transparency through digital innovation, enhanced support services, and stronger risk and security systems. In 2024, WHO strengthened its support for generating, accessing and using data paving the way for more evidence-based programming and timelier on the ground impact.

Seven countries eliminated a neglected tropical disease in 2024, reaching 54 countries that have eliminated at least one neglected tropical disease. Guinea worm disease is now closer than ever to eradication.

WHO assigned 481 international nonproprietary names for medicines and 185 countries accessed the WHO database of medical devices nomenclature.

Seventy million more people had access to mental health services by the end of 2024 and at least one million people living with a mental health condition received treatment.

An emergency polio campaign in the Gaza Strip vaccinated more than half a million children.

With support from the African Centers for Disease Control and Prevention, WHO distributed 259 000 mpox tests in 32 countries. Globally, 6 million mpox vaccine doses were pledged.

WHO coordinated responses to 51 graded emergencies in 89 countries and territories. WHO’s emergency medical teams performed more than 37 000 surgeries and supported infection prevention and control, WASH, trauma care, and mental health support.

WHO trained over 15 000 health providers and policy-makers across more than 160 Member States on addressing the health needs of refugees and migrants.

WHO collaboration with UNICEF and other UN agencies has resulted in multiyear funding programmes in 15 high-burden countries, reaching 9.3 million children and saving an estimated 1 million lives.

Increasing efficiency, the global digital health certification network supported by WHO has now enabled about 2 billion people to carry digital health records.

WHO recognizes the sustained commitment of Member States and will work with new and existing donors and partners to secure additional funding. Securing predictable, sustainable and resilient financing is the key objective of the Investment Round, which has mobilized over US$ 1.7 billion in pledges from 71 contributors, covering 53% of WHO’s voluntary funding needs.

The Results Report is crucial to WHO’s accountability to Member States. This report ensures that funding is used to deliver impact, results are regularly measured, and future needs are correctly identified, based upon lessons-learned.

The global nursing workforce has grown from 27.9 million in 2018 to 29.8 million in 2023, but wide disparities in the availability of nurses remain across regions and countries, according to the State of the World’s Nursing 2025 report, published by the World Health Organization (WHO), International Council of Nurses (ICN) and partners. Inequities in the global nursing workforce leave many of the world’s population without access to essential health services, which could threaten progress towards universal health coverage (UHC), global health security and the health-related development goals. 

The new report released on International Nurses Day provides a comprehensive and up-to-date analysis of the nursing workforce at global, regional and country levels. Consolidating information from WHO’s 194 Member States, the evidence indicates global progress in reducing the nursing workforce shortage from 6.2 million in 2020 to 5.8 million in 2023, with a projection to decline to 4.1 million by 2030. But, the overall progress still masks deep regional disparities: approximately 78% of the world’s nurses are concentrated in countries representing just 49% of the global population.  

Low- and middle-income countries are facing challenges in graduating, employing and retaining nurses in the health system and will need to raise domestic investments to create and sustain jobs. In parallel, high-income countries need to be prepared to manage high levels of retiring nurses and review their reliance on foreign-trained nurses, strengthening bilateral agreements with the countries they recruit from.   

"This report contains encouraging news, for which we congratulate the countries that are making progress,” said WHO Director-General Dr Tedros Adhanom Ghebreyesus. “However, we cannot ignore the inequalities that mark the global nursing landscape. On International Nurses Day, I urge countries and partners to use this report as a signpost, showing us where we’ve come from, where we are now, and where we need to go – as rapidly as possible.”

The State of the World’s Nursing 2025 (SoWN) report, based on data reported by 194 countries through the National Health Workforce Accounts, shows a 33% increase in the number of countries reporting data since the last edition in 2020. It includes detailed country profiles now available for public access online.

The report reveals complex disparities between and among countries, regions and socio-economic contexts. The data and evidence are intended to support country-led dialogue to contextualize the findings into policies and actions.

“We welcome the SoWN 2025 report as an important milestone for monitoring progress on strengthening and supporting the nursing workforce towards global health goals,” said Pam Cipriano, President, International Council of Nurses. “The report clearly exposes the inequalities that are holding back the nursing profession and acting as a barrier to achieving universal health coverage (UHC). Delivering on UHC is dependent on truly recognizing the value of nurses and on harnessing the power and influence of nurses to act as catalysts of positive change in our health systems.”

Gender and equity remain central concerns in the nursing workforce. Women continue to dominate the profession, making up 85% of the global nursing workforce.

Findings suggest that 1 in 7 nurses worldwide – and 23% in high-income countries – are foreign-born, highlighting reliance on international migration. In contrast, the proportion is significantly lower in upper middle-income countries (8%), lower middle-income countries (1%), and low-income countries (3%).

Low-income countries are increasing nurse graduate numbers at a faster pace than high-income countries. In many countries, hard-earned gains in the graduation rate of nurses are not resulting in improved densities due to the faster pace of population growth and lower employment opportunities.  To address this, countries should create jobs to ensure graduates are hired and integrated into the health system and improve working conditions.

Age demographics and retirement trends reveal a mixed picture. The global nursing workforce is relatively young: 33% of nurses are aged under 35 years, compared with 19% who are expected to retire in the next 10 years. However, in 20 countries – mostly high-income – retirements are expected to outpace new entrants, raising concerns about nurse shortfalls, and having fewer experienced nurses to mentor early career nurses.

Around two thirds (62%) of countries reported the existence of advanced practice nursing roles – marking significant progress since 2020 (where only 53% reported advanced practice nursing roles).  These types of nurses have been shown to expand access to and quality of care in many different settings.  

The report also highlights improvements in nursing leadership: 82% of countries reported having a senior government nursing official to manage the nursing workforce. However, leadership development opportunities remain uneven. While 66% of countries report having such initiatives in place, only 25% of low-income countries offer structured leadership development.

Mental health and workforce well-being remain areas of concern. Only 42% of responding countries have provisions for nurses’ mental health support, despite increased workloads and trauma experienced during and since the COVID-19 pandemic. Addressing this is essential to retain skilled professionals and ensure quality of care.

The report introduces forward-looking policy priorities, calling on countries to:

• expand and equitably distribute nursing jobs, especially in underserved regions;
• strengthen domestic education systems and align qualifications with defined roles;
• improve working conditions, pay equity, and mental well-being support;
• further develop nursing regulation and advanced practice nursing roles;
• promote gender equity and protect nurses working in fragile, conflict-affected settings;
• harness digital technologies and prepare nurses for climate-responsive care; and
• advance nursing leadership and ensure leadership development opportunities are equitable.

The evidence in the report provides an impetus for continued alignment to the policy priorities in the WHO Global Strategic Directions for Nursing and Midwifery 2021–2025, and the actions recommended in the resolution submitted to the 78th World Health Assembly:  Accelerating action on the health and care workforce by 2030.

Note to editors:

The State of the World’s Nursing 2025 report presents the most contemporary evidence on the global nursing workforce, including education, employment, migration, regulation, working conditions, leadership and more. The report includes updated indicators and robust estimates on global and regional-level nursing stock, shortage, and projections to 2030. Online county profiles provide national level data in a downloadable (PDF) format.  

The World Health Organization (WHO) and Medicines Patent Pool (MPP) have today announced a sublicensing agreement between MPP and a Nigerian health technology company – Codix Bio – to start development and manufacturing of rapid diagnostic tests (RDTs) using technology transferred from global in-vitro diagnostics company – SD Biosensor (SDB). This agreement will contribute to advancing equitable access to vital diagnostic tools through local production, expanding manufacturing capacity in the African Region.

The new RDT technology is especially useful for low- and middle-income countries (LMICs), as it is easy to use in health facilities without requiring additional equipment. Tests are highly sensitive and can generate results within 20 minutes. Codix Bio will initially focus on producing RDTs for HIV, but the technology can also be used for manufacturing tests for malaria and syphilis, among others. It can also be quickly adapted to other diseases, which will prove valuable during health emergencies and pandemics, contributing to improvements in health security and equity.

"Sublicensing SDB’s RDT technology marks a major milestone in strengthening manufacturing capabilities in regions where they are needed most,” said Dr Yukiko Nakatani, WHO Assistant Director-General, Access to Medicines and Health Products. “It can help advance global commitments made at the 2023 World Health Assembly to promote equitable access to diagnostics as a cornerstone of universal health coverage and pandemic preparedness.”

“We are delighted to have signed this first sublicense agreement for RDTs with Codix Bio. Today marks a major step forward in diversifying diagnostic production and ensuring access where it is needed most,” said Charles Gore, Executive Director of the Medicines Patent Pool. “It shows how voluntary licensing and coordinated technology transfer can empower manufacturers in LMICs, ultimately helping reshape global supply chains to become more equitable and resilient.”

This agreement is the first to come out of a non-exclusive, transparent license between SDB and MPP, which was agreed in December 2023 under the auspices of the WHO COVID-19 Technology Access Pool (C-TAP) initiative. C-TAP has since evolved as HTAP – the Health Technology Access Programme, with the goal of reducing the access gap in underserved regions and countries by empowering capable local producers of health products (tests, vaccines, treatments and medical devices) through sublicensing, technology and know-how transfer.

“The announcement of this sublicensing agreement with Codix Bio marks an important milestone in our partnership with WHO and MPP. By coupling the technology transfer with coordinated support, this initiative not only helps Codix Bio respond to health priorities in Nigeria and the region – it also demonstrates a collaborative model for building sustainable and self-reliant local manufacturing capacity,” said Hyo-Keun Lee, Vice Chairman of SD Biosensor, Inc. “We are proud that our highly adaptable and reliable rapid diagnostic testing technology will contribute to strengthening regional manufacturing ecosystems and expanding equitable access to diagnostics.”  

After the WHO and MPP open call was announced for applications for LMIC-based manufacturers, Codix Bio was selected as the first sublicensee. “This landmark agreement is a defining moment in our journey of health-tech innovation and a breakthrough for local healthcare manufacturing in Africa. Being selected as the first sublicensee under this global initiative underscores our commitment to contribute meaningfully to pandemic preparedness and regional health security,” said Sammy Ogunjimi, Group Managing Director/CEO, Codix Group. “With support from WHO and MPP, we are committed to producing high-quality, rapid diagnostic tests that can transform access to timely diagnosis, not just in Nigeria, but across the continent.”

HTAP will coordinate support from across WHO and its partners, covering areas such as workforce development, regulatory compliance and product uptake. It is also continuing with evaluations for a potential second sublicensee for this technology transfer.

Most LMICs rely on importing health diagnostics. Following fragility and heavy dependence on imported health product supplies during the COVID-19 pandemic and important lessons learnt for regional health security, there is growing momentum for improving local production and supply resilience, including by institutions such as the Africa Centres for Disease Control and Prevention (Africa CDC), the Global Fund and Unitaid.

"Africa CDC welcomes this partnership as a concrete example of what regional health security can look like. Building diagnostic manufacturing capacity within the continent improves pandemic response and helps build African health sovereignty. We are pleased to see Africa CDC’s strategic direction reflected in this initiative, and we stand ready to support its implementation through coordination and technical assistance,” said Dr Abebe Bayih, lead of the Platform for Harmonized African Health Manufacturing (PHAH).
 

About Medicines Patent Pool (MPP)
The Medicines Patent Pool (MPP) is a United Nations-backed public health organization working to increase access to and facilitate the development of life-saving medicines for low- and middle-income countries. Through its innovative business model, MPP partners with civil society, governments, international organizations, industry, patient groups, and other stakeholders to prioritize and license needed medicines and pool intellectual property to encourage generic manufacture and the development of new formulations. medicinespatentpool.org

About WHO
Dedicated to the well-being of all people and guided by science, the World Health Organization leads and champions global efforts to give everyone, everywhere an equal chance at a safe and healthy life. We are the UN agency for health that connects nations, partners and people on the front lines in 150+ locations – leading the world’s response to health emergencies, preventing disease, addressing the root causes of health issues and expanding access to medicines and health care. Our mission is to promote health, keep the world safe and serve the vulnerable. www.who.int

As the 8th UN Global Road Safety Week kicks off around the world under the theme “Make walking and cycling safe,” the World Health Organization (WHO) has launched a new toolkit to help governments promote active mobility – by making it safer.

Each year, nearly 1.2 million people lose their lives on the roads, more than a quarter of them while walking or cycling. Yet, only 0.2% of the roads worldwide are equipped with cycle lanes, and far too many communities lack basics like sidewalks or safe pedestrian crossings.

“Walking and cycling improve health and make cities more sustainable. Every step and every ride help to cut congestion, air pollution and disease,” said Dr Tedros Adhanom Ghebreyesus, WHO Director-General. “But we must make walking and cycling safe, so more people choose these healthier, greener options.”

Despite their benefits, fewer than one-third of countries have national policies to promote walking and cycling. WHO’s new toolkit aims to fill that gap with practical, evidence-based guidance for policymakers, urban planners, health advocates and civil society. The toolkit calls for bold action including:

• integrating walking and cycling into transport, health, environmental and education policies;
• building safe infrastructure like sidewalks, crossings and protected cycle lanes;
• setting and enforcing safer speed limits aligned with global best practices;
• promoting safe road use through public awareness and behaviour change campaigns; and
• using financial incentives to encourage active mobility.

While global pedestrian deaths dropped slightly and cyclist deaths plateaued between 2011 and 2021, regional trends show growing danger:

• In the WHO South-East Asia Region, pedestrian deaths rose by 42%.
• In the European Region, cyclist deaths surged by 50%.
• In the Western Pacific Region, cyclist deaths soared by 88%.

This week, WHO joins hundreds of organizations and governments worldwide to demand urgent action on road safety. The Global Alliance of NGOs for Road Safety is mobilizing over 400 member organizations in 100 countries to support the campaign.

“It is urgent to make, what should be our most natural means of transport, safer. This is paramount for road safety, but also health, equity and climate,” said Etienne Krug, Director of the WHO Department for the Social Determinants of Health. “We’re calling on all sectors – transport, health, education and beyond – to make walking and cycling safe and accessible for everyone.”

The Global Outbreak Alert and Response Network (GOARN), an initiative coordinated by the World Health Organization (WHO), marks its 25th anniversary today. Since its inception in April 2000, the network has been at the forefront of the global fight against health emergencies. By leveraging the expertise of global partners – facilitating alerts, deploying rapid support capacities, and strengthening capacities – it has significantly enhanced country-level operations and strengthened regional development, playing a critical role in health preparedness and response.

“GOARN is a vital part of the global health architecture,” said Dr Tedros Adhanom Ghebreyesus, WHO Director-General. “Through the network, countries get the expert support they need to respond to health emergencies, and to enhance their own capacities for preparedness and response. This means faster, more effective responses and more lives saved.”

GOARN was created in response to the need for better coordination during global health emergencies. While many partner organizations were sending teams to assist during emergencies, there was a lack of coordination which hindered the overall effectiveness of these responses. It was also clear that no single institution could address all components of a response alone. GOARN was thus born following an international meeting organized by WHO in Geneva on 26–28 April 2000. Some 121 representatives from 67 partner institutions discussed the growing challenge of epidemic-prone and emerging diseases, and the urgent need to build a global network based on existing partnerships to address these threats.

In October 2000, GOARN played a key role in responding to the major Ebola outbreak in Gulu, Uganda – marking a significant milestone in what would evolve into a quarter-century of pivotal global health responses.

“As one of the first responders deployed during the Ebola outbreak in Uganda 25 years ago, I witnessed firsthand the evolution of our response efforts and GOARN’s role,” said Dr Mike Ryan, Executive Director of WHO’s Health Emergencies Programme and Deputy Director-General of WHO.  “When I returned to Uganda earlier this year for another Ebola response, I was immensely proud to see how strong the national capacities have become, led by the Ministry of Health with the support of WHO and GOARN partners. GOARN is an example of how multilateralism works to save lives. To this day, I wear the orange GOARN lanyard alongside my blue WHO one to show my respect for and pride in this network.”

GOARN leverages the expertise of its partner institutions to address global health challenges. Operating as a unified international community, the network has responded swiftly and effectively to public health threats by deploying technical experts to ensure the right expertise is in the right place at the right time. GOARN's goal is to strengthen countries' capacities and help build strong, resilient systems for response to emergencies.

GOARN ensures that the experts are well-trained and equipped with the right skills before they’re deployed where they are needed most, fostering seamless collaboration for swift, coordinated, and impactful responses.

GOARN has now grown into a network of over 310 institutions, including national public health agencies, nongovernmental organizations, UN agencies, academic, and other technical organizations. GOARN has responded to over 175 public health emergencies in 114 countries, deploying more than 3645 international responders who integrate within national responses, collaborating with thousands of national professionals to strengthen and enhance local efforts. The network has tackled major global public health events, including outbreaks of SARS, Ebola virus disease, Marburg virus disease, COVID-19, mpox, cholera, yellow fever, disasters such as floods and earthquakes, and war. GOARN has deployed expertise in epidemiology, disease surveillance, case management, clinical care, infection prevention and control, risk communication and community engagement, and others. These efforts have also delivered hands-on training to hundreds of national teams, bolstering their immediate response capacity and long-term resilience.

"Looking back over the past 25 years, it’s remarkable to see how GOARN has evolved from a visionary concept to an indispensable network in the global health emergency landscape,” said Ray R. Arthur, PhD, Director, Global Disease Detection Operations Center, CDC (retired) and Former Chair of the GOARN Steering Committee. “As an early participant in establishing the network and as former chair of the Steering Committee, I witnessed firsthand the commitment and collaboration that drove the network’s success. GOARN has not only facilitated rapid response to public health emergencies but has also been instrumental in strengthening global health, ensuring that countries are better prepared for the challenges of tomorrow. It’s an honour to see the network continue to grow and play such a vital role in protecting public health worldwide."

Today, GOARN is a vital pillar in the Global Health Emergency Corps ensuring a well-coordinated health emergency workforce, centered in countries and connected regionally and globally. The 25-year milestone marks a significant evolution of GOARN’s role in preparedness and response. Rather than deploying large numbers of international professionals across every field, GOARN now brings in only the necessary expertise to address critical gaps on the ground. Paired with the focus on capacity strengthening and training initiates, GOARN has demonstrated the effectiveness of its mandate and efforts empowering countries to manage emergencies themselves.

GOARN calls on all Member States, partners and the global community to continue working together to build a global health emergency architecture that is resilient, equitable, and capable of addressing future health challenges.
 

Dr Mohannad Al-Nsour, Executive Director, Eastern Mediterranean Public Health Network (EMPHNET), current Chair of the GOARN Steering Committee:
“As the world faces the growing threats of epidemics, conflict, and humanitarian crises, GOARN’s role has never been more vital. The network is being called to respond in increasingly complex environments – where conflict is more widespread, and public health emergencies unfold alongside deep humanitarian challenges. GOARN must continue to evolve, expanding its reach and strengthening collaboration to meet these urgent needs.”

Daniela Garone, Infectious Diseases Specialist and International Medical Coordinator, Médecins Sans Frontières, current Co-Deputy Chairs of the GOARN Steering Committee and Dr Edmund Newman, Director, UK Public Health Rapid Support Team (UK-PHRST):
"Reflecting on GOARN’s 25 years of advancing global health emergency preparedness and response, we are proud to be active partners of a network that has been instrumental in saving lives and strengthening health response systems around the world. From its humble beginnings to its current role as a vital pillar in global health response, GOARN has demonstrated the power of collaboration and expertise in tackling public health emergencies. As we look to the future, we remain committed to supporting countries in building resilient public health systems and ensuring that our collective efforts continue to evolve in response to the growing challenges of global health. Together, we will continue to foster stronger partnerships and be ready for whatever comes next."

Myriam Henkens MD, MPH, Senior Health Adviser, Médecins Sans Frontières, former member of GOARN Steering Committee:
“For 25 years, GOARN has been a cornerstone in the global response to health emergencies. As a proud participant, MSF has been working alongside GOARN to strengthen health systems and ensure a more effective global response to the challenges of tomorrow. The collaborative spirit and shared expertise across the network have made a real difference in the field, and I’m proud to have been part of this journey.”

Gail Carson, Director of Network Development at ISARIC Pandemic Sciences Institute, University of Oxford and former Chair of the GOARN Steering Committee (2022–2024):
“Serving as Chair of the GOARN Steering Committee from 2022 to 2024 was one of the greatest honours of my career. But my connection to this network goes back much further—to GOARN’s first response to Ebola in Uganda. Over the past 25 years, I’ve seen firsthand how this global community of experts supports countries in times of crisis, delivering trusted, timely, and lifesaving technical assistance. Today, GOARN continues to evolve to meet new and complex challenges. What hasn’t changed is its core strength: GOARN remains the partner you can count on when a health emergency hits.”

John S Mackenzie, Emeritus Professor and former Chair of the GOARN Steering Committee:
“GOARN was born from a visionary belief that global outbreak response could be stronger through coordinated action. I was proud to serve on its first Steering Committee, and those 14 years remain among the most fulfilling of my career. GOARN continues to grow as a powerful force in global public health – driven by collaboration, expertise, and an enduring spirit of service.”

Pat Drury, former GOARN Manager:
“GOARN has been more than just a professional milestone—it has been a journey of saving lives and making a real difference in the face of some of the world’s most challenging outbreaks, from Ebola, and SARS to COVID-19. The network’s strength is its ability to connect people, and institutions, knowledge and expertise in real time, turning alerts into rapid responses. As the challenges have grown, so have the stakes. In an increasingly polarised world, GOARN’s role in mobilizing science, and fostering trust has never been more vital. Congratulations on 25 years of extraordinary impact, and thank you to the countless individuals who make this mission possible.”

On World Malaria Day, the World Health Organization (WHO) is calling for revitalized efforts at all levels, from global policy to community action, to accelerate progress towards malaria elimination.

In the late 1990s, world leaders laid the foundation for remarkable progress in global malaria control, including preventing more than 2 billion cases of malaria and nearly 13 million deaths since 2000.

To date, WHO has certified 45 countries and 1 territory as malaria-free, and many countries with a low burden of malaria continue to move steadily towards the goal of elimination. Of the remaining 83 malaria-endemic countries, 25 reported fewer than 10 cases of the disease in 2023.

However, as history has shown, these gains are fragile.

“The history of malaria teaches us a harsh lesson: when we divert our attention, the disease resurges, taking its greatest toll on the most vulnerable,” said WHO Director-General Dr Tedros Adhanom Ghebreyesus. “But the same history also shows us what’s possible: with strong political commitment, sustained investment, multisectoral action and community engagement, malaria can be defeated.”

Years of investment in the development and deployment of new malaria vaccines and next-generation tools to prevent and control malaria are paying off.

On World Malaria Day, Mali will join 19 other African countries in introducing malaria vaccines—a vital step towards protecting young children from one of the continent’s most deadly diseases. The large-scale rollout of malaria vaccines in Africa is expected to save tens of thousands of young lives every year.

Meanwhile, the expanded use of a new generation of insecticide-treated nets is poised to lower the disease burden. According to the latest World malaria report, these new nets—which have greater impact against malaria than the standard pyrethroid-only nets—accounted for nearly 80% of all nets delivered in sub-Saharan Africa in 2023, up from 59% the previous year.

Despite significant gains, malaria remains a major public health challenge, with nearly 600 000 lives lost to the disease in 2023 alone. The African Region is hardest hit, shouldering an estimated 95% of the malaria burden each year.

In many areas, progress has been hampered by fragile health systems and rising threats such as drug and insecticide resistance. Many at-risk groups continue to miss out on the services they need to prevent, detect and treat malaria. Climate change, conflict, poverty and population displacement are compounding these challenges.

WHO recently warned that the 2025 funding cuts could further derail progress in many endemic countries, putting millions of additional lives at risk. Of the 64 WHO Country Offices in malaria-endemic countries that took part in a recent WHO stock take assessment, more than half reported moderate or severe disruptions to malaria services.

World Malaria Day 2025 - under the theme, “Malaria ends with us: reinvest, reimagine, reignite” - is calling for stepped up political and financial commitment to protect the hard-won gains against malaria.

To reinvest, WHO joins partners and civil society in calling on malaria-endemic countries to boost domestic spending, particularly in primary health care, so that all at-risk populations can access the services they need to prevent, detect and treat malaria. The successful replenishments of the Global Fund and Gavi, the Vaccine Alliance, are also critical to financing malaria programmes and interventions, and accelerating progress towards the targets set in the WHO Global technical strategy for malaria 2016-2030.

Addressing current challenges in global malaria control will also require a reimagined response through innovative tools, strategies and partnerships. New and more effective antimalarial drugs are needed, as all well as advancements in service delivery, diagnostics, insecticides, vaccines and vector control methods.

More countries are making malaria control and elimination a national priority, including through the Yaoundé Declaration, signed in March 2024 by African Ministers of Health from 11 high burden countries.

“Ministers committed to strengthening their health systems, stepping up domestic resources, enhancing multisectoral action and ensuring a robust accountability mechanism,” notes Dr Daniel Ngamije, Director of the WHO Global Malaria Programme. “This is the kind of leadership the world must rally behind.”

Reigniting commitment at all levels – from communities and frontline health workers to governments, researchers, the private sector innovators and donors – will be critical to curbing and, ultimately, ending malaria.

Notes to the editor:

For more information on the WHO World Malaria Day campaign, visit: https://www.who.int/campaigns/world-malaria-day/2025

Immunization efforts are under growing threat as misinformation, population growth, humanitarian crises and funding cuts jeopardize progress and leave millions of children, adolescents and adults at risk, warn WHO, UNICEF, and Gavi during World Immunization Week, 24–30 April.

Outbreaks of vaccine-preventable diseases such as measles, meningitis and yellow fever are rising globally, and diseases like diphtheria, that have long been held at bay or virtually disappeared in many countries, are at risk of re-emerging. In response, the agencies are calling for urgent and sustained political attention and investment to strengthen immunization programmes and protect significant progress achieved in reducing child mortality over the past 50 years.

“Vaccines have saved more than 150 million lives over the past five decades,” said WHO Director-General, Dr Tedros Adhanom Ghebreyesus. “Funding cuts to global health have put these hard-won gains in jeopardy. Outbreaks of vaccine-preventable diseases are increasing around the world, putting lives at risk and exposing countries to increased costs in treating diseases and responding to outbreaks. Countries with limited resources must invest in the highest-impact interventions – and that includes vaccines.”

Measles is making an especially dangerous comeback. The number of cases has been increasing year on year since 2021, tracking the reductions in immunization coverage that occurred during and since the COVID-19 pandemic in many communities. Measles cases reached an estimated 10.3 million in 2023, a 20% increase compared to 2022.

The agencies warn that this upward trend likely continued into 2024 and 2025, as outbreaks have intensified around the world. In the past 12 months, 138 countries have reported measles cases, with 61 experiencing large or disruptive outbreaks – the highest number observed in any 12-month period since 2019.

Meningitis cases in Africa also rose sharply in 2024, and the upward trend has continued into 2025. In the first three months of this year alone, more than 5500 suspected cases and nearly 300 deaths were reported in 22 countries. This follows approximately 26 000 cases and almost 1400 deaths across 24 countries last year.

Yellow fever cases in the African region are also climbing, with 124 confirmed cases reported in 12 countries in 2024. This comes after dramatic declines in the disease over the past decade, thanks to global vaccine stockpiles and use of yellow fever vaccine in routine immunization programmes. In the WHO Region of the Americas, yellow fever outbreaks have been confirmed since the beginning of this year, with a total of 131 cases in 4 countries.

These outbreaks come amidst global funding cuts. A recent WHO rapid stock take with 108 country offices of WHO – mostly in low- and lower-middle-income countries – shows that nearly half of those countries are facing moderate to severe disruptions to vaccination campaigns, routine immunization and access to supplies due to reduced donor funding. Disease surveillance, including for vaccine-preventable diseases, is also impacted in more than half of the countries surveyed.

At the same time, the number of children missing routine vaccinations has been increasing in recent years, even as countries make efforts to catch up children missed during the pandemic. In 2023, an estimated 14.5 million children missed all of their routine vaccine doses – up from 13.9 million in 2022 and 12.9 million in 2019. Over half of these children live in countries facing conflict, fragility, or instability, where access to basic health services is often disrupted.

“The global funding crisis is severely limiting our ability to vaccinate over 15 million vulnerable children in fragile and conflict-affected countries against measles,” said UNICEF Executive Director Catherine Russell. “Immunization services, disease surveillance, and the outbreak response in nearly 50 countries are already being disrupted – with setbacks at a similar level to what we saw during COVID-19. We cannot afford to lose ground in the fight against preventable diseases.”

Continued investment in the ‘Big Catch-Up initiative’, launched in 2023 to reach children who missed vaccines during the COVID-19 pandemic, and other routine immunization programmes will be critical.

Joint efforts by WHO, UNICEF, Gavi and partners have helped countries expand access to vaccines and strengthen immunization systems through primary health care, even in the face of mounting challenges. Every year, vaccines save nearly 4.2 million lives against 14 diseases – with nearly half of these lives saved in the African Region.

Vaccination campaigns have led to the elimination of meningitis A in Africa’s meningitis belt, while a new vaccine that protects against five strains of meningitis holds promise for broader protection, with efforts underway to expand its use for outbreak response and prevention.

Progress has also been made in reducing yellow fever cases and deaths through increasing routine immunization coverage and emergency vaccine stockpiles, but recent outbreaks in Africa and in the Region of the Americas highlight the risks in areas with no reported cases in the past, low routine vaccination coverage and gaps in preventive campaigns.

In addition, the past two years have seen substantial progress in other areas of immunization. In the African Region, which has the highest cervical cancer burden in the world, HPV vaccine coverage nearly doubled between 2020 and 2023 from 21% to 40%, reflecting a concerted global effort towards eliminating cervical cancer. The progress in immunization also includes increases in global coverage of pneumococcal conjugate vaccines, particularly in the South-East Asia Region, alongside introductions in Chad and Somalia, countries with high disease burden.

Another milestone is the sub-national introduction of malaria vaccines in nearly 20 African countries, laying the foundation to save half a million additional lives by 2035 as more countries adopt the vaccines and scale-up accelerates as part of the tools to fight malaria.

UNICEF, WHO, and Gavi urgently call for parents, the public, and politicians to strengthen support for immunization. The agencies emphasize the need for sustained investment in vaccines and immunization programmes and urge countries to honour their commitments to the Immunization Agenda 2030 (IA2030).

As part of integrated primary health-care systems, vaccination can protect against diseases and connect families to other essential care, such as antenatal care, nutrition or malaria screening. Immunization is a ‘best buy’ in health with a return on investment of $54 for every dollar invested and provides a foundation for future prosperity and health security.

“Increasing outbreaks of highly infectious diseases are a concern for the whole world. The good news is we can fight back, and Gavi’s next strategic period has a clear plan to bolster our defences by expanding investments in global vaccine stockpiles and rolling out targeted preventive vaccination in countries most impacted by meningitis, yellow fever and measles,” said Dr Sania Nishtar, CEO of Gavi, the Vaccine Alliance. “These vital activities, however, will be at risk if Gavi is not fully funded for the next five years and we call on our donors to support our mission in the interests of keeping everyone, everywhere, safer from preventable diseases.”

Gavi’s upcoming high-level pledging summit taking place on 25 June 2025 seeks to raise at least US$ 9 billion from our donors to fund our ambitious strategy to protect 500 million children, saving at least 8 million lives from 2026–2030.

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Notes to editor:

Download multimedia content here: https://weshare.unicef.org/Package/2AM4086M4S1G

About WHO
Dedicated to the health and well-being of all people and guided by science, the World Health Organization leads and champions global efforts to give everyone, everywhere, an equal chance at a safe and healthy life. We are the UN agency for health. We connect nations, partners and people on the front lines in 150+ locations – leading the world’s response to health emergencies, preventing disease, addressing the root causes of health issues and expanding access to medicines and health care. Our mission is to promote health, keep the world safe and serve the vulnerable. www.who.int

About UNICEF
UNICEF works in some of the world's toughest places, to reach the world's most disadvantaged children. Across more than 190 countries and territories, we work for every child, everywhere, to build a better world for everyone. For more information about UNICEF and its work, visit: www.unicef.org.

About Gavi, the Vaccine Alliance
Gavi, the Vaccine Alliance is a public-private partnership that helps vaccinate more than half the world’s children against some of the world’s deadliest diseases. Since its inception in 2000, Gavi has helped to immunize a whole generation – over 1.1 billion children – and prevented more than 18.8 million future deaths, helping to halve child mortality in 78 lower income countries. Gavi also plays a key role in improving global health security by supporting health systems as well as funding global stockpiles for Ebola, cholera, meningococcal and yellow fever vaccines. After two decades of progress, Gavi is now focused on protecting the next generation, above all the zero-dose children who have not received even a single vaccine shot. The Vaccine Alliance employs innovative finance and the latest technology – from drones to biometrics – to save lives, prevent outbreaks before they can spread and help countries on the road to self-sufficiency. Learn more at www.gavi.org.

In a bid to tackle the leading cause of death globally among 15–19-year-old girls, the World Health Organization (WHO) today released a new guideline aimed at preventing adolescent pregnancy and its significant related health complications.

Among other strategies, the guideline urges rapid action to end child marriage, extend girls’ schooling, and improve access to sexual and reproductive health services and information – all critical factors for reducing early pregnancies among teenagers around the world.

“Early pregnancies can have serious physical and psychological consequences for girls and young women, and often reflect fundamental inequalities that affect their ability to shape their relationships and their lives,” said Dr Pascale Allotey, Director of Sexual and Reproductive Health and Research at WHO and the United Nations’ Special Programme in Human Reproduction (HRP). “Tackling this issue therefore means creating conditions where girls and young women can thrive – by ensuring they can stay in school, be protected from violence and coercion, access sexual and reproductive health services that uphold their rights, and have real choices about their futures.”

More than 21 million adolescent girls become pregnant each year in low and middle-income countries, around half of which are unintended. With impacts on girls’ education, social connection and future employment prospects, early pregnancy can create cycles of intergenerational poverty that become difficult to break. It also brings serious health risks, including relatively higher rates of infections and preterm births as well as complications from unsafe abortions – linked to particular challenges in accessing safe and respectful care.

Reasons for early pregnancy are varied and interrelated, including gender inequities, poverty, lack of opportunity and inability to access sexual and reproductive health services. There is a strong correlation with child marriage: in low- and middle-income countries, 9 in 10 adolescent births take place among girls who were married before the age of 18.

The guideline recommends holistic efforts to provide viable alternatives to early marriage by strengthening girls’ education, savings and employment prospects. If all girls finished their secondary schooling, it has been estimated that child marriages could be reduced by as much as two thirds. For girls at highest risk, the guideline recommends considering incentives to support secondary school completion, such as targeted financial stipends or scholarship programmes. The guideline also recommends laws to prohibit marriage below the age of 18, consistent with human rights standards, and community engagement to prevent the practice.

“Early marriage denies girls their childhood and has severe consequences for their health,” said Dr Sheri Bastien, Scientist for Adolescent Sexual and Reproductive Health at WHO. “Education is critical to change the future for young girls, while empowering adolescents – both boys and girls – to understand consent, take charge of their health, and challenge the major gender inequalities that continue to drive high rates of child marriage and early pregnancy in many parts of the world.”

The recommendations highlight the need to ensure adolescents can access high quality, adolescent-responsive sexual and reproductive health services including contraceptive options. In some countries, consent from an adult is required to access services, which is a significant barrier to their use. Young girls who get pregnant also need to be able to access high quality and respectful healthcare during and after pregnancy and birth, free from stigma and discrimination, as well as safe abortion care.

Finally, comprehensive sexuality education is essential for both boys and girls to ensure they know where to access such services and how to use different types of contraception. It has been shown to reduce early pregnancies, delay the onset of sexual activity, and improve adolescents’ knowledge about their bodies and reproductive health. 

This guideline updates an earlier edition of the guideline on adolescent pregnancy prevention from 2011 and focuses particularly on preventing child marriage and improving adolescents’ access to and use of contraception. It complements WHO’s related guidance around health services for adolescents, comprehensive sexuality education and gender-based violence.

Globally, there has been progress in reducing adolescent pregnancies and births. In 2021, an estimated 1 in 25 girls gave birth before the age of 20, compared to 1 in 15 two decades prior. There remain significant disparities. In some countries, close to 1 in 10 adolescent girls (15–19 years) give birth each year.

Africa CDC and WHO have updated their joint Continental Response Plan for the mpox emergency as the disease continues to affect new areas. The revised strategy focuses on controlling outbreaks, while expanding vaccination coverage and transitioning toward a longer-term, sustainable response. 

Mpox is a viral illness that spreads between people, mainly through close contact. It causes painful skin and mucosal lesions, often accompanied by fever, headache, muscle aches, back pain, fatigue, and swollen lymph nodes. The disease can be debilitating and disfiguring. 

Historically a zoonotic disease transmitted from infected animals, mpox has increasingly shown a tendency to spread between people. In 2022, a variant of the virus, clade IIb, began spreading globally through sexual contact. Since late 2023, yet another viral strain, clade Ib, began spreading through sexual networks and within households and through close contact. This prompted Africa CDC to declare a Public Health Emergency of Continental Security and the WHO Director-General to declare a Public Health Emergency of International Concern in August 2024. 

By August 2024, the virus had begun spreading from the Democratic Republic of the Congo to 4 neighbouring countries. Since then, 28 countries around the world have reported cases of mpox due to clade Ib. Outside Africa, cases remain largely travel-related. However, within Africa, in addition to transmission in Burundi, the Democratic Republic of the Congo, Kenya, Rwanda and Uganda, local transmission has now been documented in additional countries including the Republic of the Congo, South Africa, South Sudan, the United Republic of Tanzania and Zambia. 

Since the declaration of the emergency, both regional and global support has increased, particularly for the Democratic Republic of the Congo, the epicentre of the outbreak. The Africa CDC and WHO Joint Continental Mpox Plan has guided these efforts, focusing on ten key pillars: coordination, risk communication and community engagement, disease surveillance, laboratory capacity, clinical management, infection prevention and control, vaccination, research, logistics, and maintaining essential health services. 

Vaccination efforts are underway, with more than 650 000 doses administered in 6 countries, 90% of which have been administered in the Democratic Republic of the Congo. Overall, over a million doses have been delivered to 10 countries, with efforts ongoing to secure additional vaccine supplies. 

Diagnostic testing capacity in the Democratic Republic of the Congo has grown significantly, driven by the expansion of laboratory infrastructure - from 2 laboratories in late 2023 to 23 laboratories in 12 provinces today. With new, near-point-of-care tests currently being rolled out in the country, capacity is expected to increase even further. 

Despite this progress, major challenges remain. Ongoing conflict and insecurity in eastern Democratic Republic of the Congo, where the incidence of mpox remains high, as well as humanitarian aid cuts, continue to limit the public health response and restrict access to essential services. Across countries and partners, over US$ 220 million is needed to fill funding gaps for the mpox response.  

The updated Continental Response Plan calls for intensified efforts to bring outbreaks under control, while also taking concrete actions to integrate mpox into routine health services.  

Along with the Continental Response Plan for Africa, WHO has updated the global strategic plan to curb - and where feasible, to stop - human-to-human transmission of mpox. In the first two months of 2025, 60 countries reported mpox, with the majority of cases and deaths reported from the African continent.  The joint Continental Response Plan is aligned with the global strategy. 

Africa CDC and WHO continue to work closely with national governments, local communities, and partners to curb transmission, control the outbreak, and build longer-term resilience within public health systems. 

After more than three years of intensive negotiations, WHO Member States took a major step forward in efforts to make the world safer from pandemics, by forging a draft agreement for consideration at the upcoming World Health Assembly in May. The proposal aims to strengthen global collaboration on prevention, preparedness and response to future pandemic threats.

In December 2021, at the height of the COVID-19 pandemic, WHO Member States established the Intergovernmental Negotiating Body (INB) to draft and negotiate a convention, agreement or other international instrument, under the WHO Constitution, to strengthen pandemic prevention, preparedness and response.

Following 13 formal rounds of meetings, nine of which were extended, and many informal and intersessional negotiations on various aspects of the draft agreement, the INB today finalized a proposal for the WHO Pandemic Agreement. The outcome of the INB’s work will now be presented to the Seventy-eighth World Health Assembly for its consideration.

"The nations of the world made history in Geneva today," said Dr Tedros Adhanom Ghebreyesus, WHO Director-General. "In reaching consensus on the Pandemic Agreement, not only did they put in place a generational accord to make the world safer, they have also demonstrated that multilateralism is alive and well, and that in our divided world, nations can still work together to find common ground, and a shared response to shared threats. I thank WHO's Member States, and their negotiating teams, for their foresight, commitment and tireless work. We look forward to the World Health Assembly's consideration of the agreement and – we hope – its adoption."

Proposals within the text developed by the INB include establishing a pathogen access and benefit sharing system; taking concrete measures on pandemic prevention, including through a One Health approach; building geographically diverse research and development capacities; facilitating the transfer of technology and related knowledge, skills and expertise for the production of pandemic-related health products; mobilizing  a skilled, trained and multidisciplinary national and global health emergency workforce; setting up a coordinating financial mechanism; taking concrete measures to strengthen preparedness, readiness and health system functions and resilience; and establishing a global supply chain and logistics network.

The proposal affirms the sovereignty of countries to address public health matters within their borders, and provides that nothing in the draft agreement shall be interpreted as providing WHO any authority to direct, order, alter or prescribe national laws or policies, or mandate States to take specific actions, such as ban or accept travellers, impose vaccination mandates or therapeutic or diagnostic measures or implement lockdowns.

Dr Tedros paid tribute to the members of the Bureau who guided the INB process: Co-Chairs Ms Precious Matsoso (South Africa) and Ambassador Anne-Claire Amprou (France), and Vice-Chairs Ambassador Tovar da Silva Nunes (Brazil), Ambassador Amr Ramadan (Egypt), Dr Viroj Tangcharoensathien (Thailand); and Ms Fleur Davies (Australia). Past members included former Co-Chair, Mr Roland Driece (the Netherlands), and former Vice-Chairs Ambassador Honsei Kozo (Japan), Mr Kazuho Taguchi (Japan), and Mr Ahmed Soliman (Egypt). The Director-General also acknowledged the constant support provided by WHO Secretariat colleagues.

INB Co-Chair Ms Matsoso said: “I am overjoyed by the coming together of countries, from all regions of the world, around a proposal to increase equity and, thereby, protect future generations from the suffering and losses we suffered during the COVID-19 pandemic. The negotiations, at times, have been difficult and protracted. But this monumental effort has been sustained by the shared understanding that viruses do not respect borders, that no one is safe from pandemics until everyone is safe, and that collective health security is an aspiration we deeply believe in and want to strengthen.”

Fellow INB Co-Chair, Ambassador Amprou, said the draft agreement is a major step in strengthening the global health security architecture so people of the world would be better protected from the next pandemic.

“In drafting this historic agreement, the countries of the world have demonstrated their shared commitment to preventing and protecting everyone, everywhere, from future pandemic threats,” Ambassador Amprou said. “While the commitment to prevention through the One Health approach is a major step forward in protecting populations, the response will be faster, more effective and more equitable. This is a historic agreement for health security, equity and international solidarity.”

The INB was established in December 2021, at a special session of the World Health Assembly, bringing together Member States and relevant stakeholders, including international organizations, private sector, and civil society. At the World Health Assembly in June 2024, governments made concrete commitments to complete negotiations on a global pandemic agreement within a year. The upcoming Assembly starting 19 May 2025 will consider the proposal developed by the INB and take the final decision on whether to adopt the instrument under Article 19 of the WHO Constitution.

The World Health Organization (WHO) issues warning on health service disruptions reported in 70% of its surveyed country offices as a result of sudden suspensions and reductions in official development assistance (ODA) for health.

The findings, based on rapid WHO assessment of the fast-evolving situation, raise concern for potentially deeper and prolonged effects on health systems and services across the world, especially in vulnerable and fragile settings. This requires urgent action and international response.

The new rapid stock take conducted in March–April 2025 with 108 WHO country offices, primarily in low- and lower-middle-income countries, shows that many countries are working to increase or reallocate funding from domestic and alternative external sources to address gaps. However, up to 24% of WHO Country Office responses suggest budget cuts are already translating into increased out-of-pocket payments. The poor and vulnerable likely risk bearing the additional brunt of these impacts.

“These results paint a worrying picture about the impact of the sudden and unplanned cuts to aid on the health of millions of people,” said Dr Tedros Adhanom Ghebreyesus, WHO Director-General. “Although these cuts are a shock, they are also driving an accelerated transition away from aid dependency to a more sustainable self-reliance, based on domestic resources. Many countries are asking for WHO’s support, and WHO is working with them to identify and tailor the most effective measures.”

The stock take reports provide an early snapshot and insights from WHO country offices that work closely with ministries of health, providing regular support on health systems policies and planning. The stock take aimed at identifying the urgent support countries need to avoid catastrophic impacts on the health of the populations and to guide monitoring of the rapidly evolving situation. 

Key findings from the stock take show the following.

• The suspensions and reductions in ODA are disrupting all health system functions, with the most frequently reported impacts being on health emergency preparedness and response (70%), public health surveillance (66%), service provision (58%), humanitarian aid (56%), and the health and care workforce (54%).
• Health services are being disrupted across the board in at least one third of the responding countries, with high levels of disruptions reported in outbreak detection and response, malaria, HIV, tuberculosis, sexually transmitted infections, family planning, and maternal and child health services.
• The nature and scale of service disruptions are comparable to those observed during the peak periods of the COVID-19 pandemic in some settings. 
• Critical shortages in the availability of medicines and health products are leaving one third of responding countries without commodities for major service areas.
• The pause in ODA has led to job losses for health and care workers in over half of responding countries, and significant disruptions to trainings.

• Information systems are particularly impacted as key health data collection is disrupted. Over 40% of countries experienced disruptions to key information systems, including collaborative surveillance and emergency systems, health management information systems, disease-specific reporting systems, lab information systems, and household/population surveys.
• Eighty-one of the 108 WHO country offices have expressed the need for support across a broad range of health areas, including innovative funding and resource mobilization, targeted technical assistance and support.

Given the rapidly evolving context, WHO will be monitoring the situation over time and will engage the global health community, including partners and donor agencies, to inform urgent response plans to mitigate deepening country impacts and enable greater sustainability.  

Note to editors:

These findings represent a snapshot of the health systems and health services situation in the context of a rapidly evolving situation. Senior WHO country office staff were surveyed over the period of 7 March to 2 April 2025 to provide inputs and observations on the impact of ODA suspensions and reductions through a structured survey. WHO country offices in low- and lower-middle-income countries across all six WHO regions were included in this survey. They do not reflect the official views of the governments in the countries, territories and areas. WHO has a global presence in 150+ locations putting central focus on countries and populations, working to protect and improve the health of everyone, everywhere. More information.

The World Health Organization (WHO) has today published its first-ever global guidelines for meningitis diagnosis, treatment and care, aiming to speed up detection, ensure timely treatment, and improve long-term care for those affected. By bringing together the latest evidence-based recommendations, the guidelines provide a critical tool for reducing deaths and disability caused by the disease.

Despite effective treatments and vaccines against some forms of meningitis, the disease remains a significant global health threat. Bacterial meningitis is the most dangerous form and can become fatal within 24 hours. Many pathogens can cause meningitis with an estimated 2.5 million cases reported globally in 2019. This includes 1.6 million cases of bacterial meningitis which resulted in approximately 240 000 deaths.

Around 20% of people who contract bacterial meningitis develop long-term complications, including disabilities that impact quality of life. The disease also carries heavy financial and social costs for individuals, families, and communities.

“Bacterial meningitis kills one in six of the people it strikes, and leaves many others with lasting health challenges," said Dr Tedros Adhanom Ghebreyesus, WHO Director-General. "Implementing these new guidelines will help save lives, improve long-term care for those affected by meningitis, and strengthen health systems."

Meningitis can affect anyone anywhere, and at any age, however the disease burden remains particularly high in low- and middle-income countries and in settings experiencing large-scale epidemics.  The highest burden of disease is seen in a region of sub-Saharan Africa, often referred to as the ‘meningitis belt’, which is at high risk of recurrent epidemics of meningococcal meningitis.

Improving clinical management of meningitis is essential to reducing mortality and morbidity, minimizing long-term complications and disability, and improving quality of life for affected individuals and communities.

The new guidelines provide evidence-based recommendations for the clinical management of children over one month of age, adolescents, and adults with acute community-acquired meningitis.

They address all aspects of clinical care, including diagnosis, antibiotic therapy, adjunctive treatment, supportive care, and management of long-term effects.  Given the similarities in clinical presentation, diagnosis and management approaches across different forms of acute community-acquired meningitis, the guidelines address both bacterial and viral causes.

The guidelines provide recommendations for both non-epidemic and epidemic settings, the latter superseding previous 2014 WHO guidelines, which covered  meningitis outbreak response.

As resource-limited settings bear the highest burden of meningitis, these guidelines have been specifically developed to provide technical guidance suitable for implementation in low- and middle-income countries.

The guidelines are intended for use by health-care professionals in first- and second-level facilities, including emergency, inpatient, and outpatient services. Policymakers, health planners, academic institutions, and civil society organizations can also use them to inform capacity-building, education, and research efforts.

The guidelines contribute to the broader Defeating Meningitis by 2030 Global Roadmap, adopted by WHO Member States in 2020, which aims to: eliminate bacterial meningitis epidemics, reduce cases of vaccine-preventable bacterial meningitis by 50% and deaths by 70%, and reduce disability and improve quality of life after meningitis.

Achieving these goals requires coordinated action across five key areas:

1. Diagnosis and treatment: Faster detection and optimal clinical management.
2. Prevention and epidemic control: Developing new affordable vaccines, achieving high immunization and coverage, and improving outbreak preparedness and response.
3. Disease surveillance: Strengthening monitoring systems to guide prevention and control.
4. Care and support for those affected by meningitis: Ensuring early recognition and improved access to care and support for after-effects from meningitis. 
5. Advocacy and engagement: Increasing political commitment and inclusion in country plans, better public understanding of meningitis, and increased awareness of right to prevention, care and after-care services.

With these guidelines, WHO provides countries with a critical tool to close gaps in meningitis diagnosis, treatment and care, ensuring that more people receive timely treatment and long-term support.